Semmler is a German surname. Notable people with the surname include:
Christoph Semmler (born 1980), German footballer Clement Semmler, (1914–2000), Australian author, literary critic, broadcaster and radio and television executive Friedrich Wilhelm Semmler (1836–1931), German chemist Rudolf Semmler (1913-?), journalist Stefan Semmler (born 1952), German rower
See also Semmler-Wolff reaction Semler