Sesay is a common surname among the Mandingo, Temne, Loko, Limba and Kuranko people of Sierra Leone, and may refer to:
Alimamy Sesay (1987–), Sierra Leonean football player Ansu Sesay (1976–), American professional basketball player Benjamin Sesay (1981–), Sierra Leonean international football player Brima Sesay (1981–2009), Sierra Leonean international football goalkeeper David Sesay (1998–), British football player Hassan Koeman Sesay (1986–), Sierra Leonean international football player Hassan Mila Sesay (1987–), Sierra Leonean international football player Ibrahim Sesay, member of parliament of Sierra Leone Isha Sesay, British journalist of Sierra Leonean descent and anchor of CNN International Issa Hassan Sesay (1970–), served as senior officer and commander in the Revolutionary United Front and AFRC/RUF forces in their insurrection against the government of Sierra Leone Kadi Sesay, formally Kadiatu Sesay, former Sierra Leone Minister of Trade and Industry and mother of CNN International anchor Isha Sesay Kadija Sesay, also called Kadija George, is a British writer and poet of Sierra Leonean descent Lamin-Sullay Sesay (1965–2004), also called , Sierra Leonean writer and journalist Maria Sesay, Sierra Leonean media host and culture curator Muwahid Sesay (1984–), Sierra Leonean international football striker Sulaiman Sesay Fullah, Sierra Leonean international footballer Zainab Bangura (born Zainab Hawa Sesay, 1959–), Sierra Leone minister of foreign affairs