Dushku is an Albanian surname. Notable people with the surname include:

Eliza Dushku (born 1980), American actress and producer Erjon Dushku (born 1985), Albanian footballer Judy Dushku (born 1942), American academic political scientist, journalist, writer, and humanitarian Nate Dushku (born 1977), American director, producer, and actor Rigers Dushku (born 1991), Albanian footballer