Locust Grove is the name of a number of places in the United States of America:
Arkansas Locust Grove, Arkansas
Georgia Locust Grove, Georgia
Indiana Locust Grove, Warren County, Indiana (extinct)
Kentucky Locust Grove, Clark County, Kentucky Locust Grove, Pendleton County, Kentucky Historic Locust Grove, near Louisville, Kentucky
Maryland Locust Grove (La Plata, Maryland), listed on the NRHP in Charles County, Maryland five places named Locust Grove: two places in Garrett County, Maryland in Kent County, Maryland in Allegany County, Maryland in Washington County, Maryland
New Jersey Locust Grove, New Jersey
New York Locust Grove, New York (a section of Syosset, New York): Locust Grove (Poughkeepsie, New York), listed on the NRHP in Dutchess County, New York, also known as Samuel F. B. Morse House
North Carolina Locust Grove (Ingleside, North Carolina), listed on the NRHP in North Carolina
Ohio Locust Grove, Adams County, Ohio Locust Grove, Licking County, Ohio Locust Grove, Mahoning County, Ohio
Oklahoma Locust Grove, Oklahoma
Oregon Locust Grove, Oregon, a ghost town
Pennsylvania Locust Grove (Bainbridge, Pennsylvania), listed on the NRHP in Pennsylvania Locust Grove, Pennsylvania (four places): in Centre County in Lancaster County in Snyder County in York County
Tennessee Locust Grove, Tennessee Locust Grove (Castalian Springs, Tennessee), listed on the NRHP in Tennessee
Texas Locust Grove (Jonesville, Texas)
Virginia Locust Grove (Amicus, Virginia), listed on the NRHP in Virginia Locust Grove (Dillwyn, Virginia), listed on the NRHP in Virginia Locust Grove (Charlottesville, Virginia), listed on the NRHP in Virginia Locust Grove (Lynchburg, Virginia), listed on the NRHP in Virginia Locust Grove, Orange County, Virginia Locust Grove (Page County, Virginia), a historic house Locust Grove (Purcellville, Virginia), listed on the NRHP in Virginia Locust Grove (Rapidan, Virginia), listed on the NRHP in Virginia Locust Grove, Shenandoah County, Virginia