Class 27 may refer to:
Belgian Railways Class 27, electric locomotive British Rail Class 27, diesel locomotive EAR 27 class, steam locomotive GER Class D27, steam locomotive L&YR Class 27, steam locomotive PKP class OKl27, steam locomotive Rio Grande class K-27, steam locomotive SNCB Class 27, electric locomotive U-27-class submarine (disambiguation)
See also Type 27 (disambiguation)