X8 or X-8 may refer to:

Arts and entertainment Mega Man X8, a video game Rockman X8 Original Soundtrack, the music of the video game WrestleMania X8, a catch event WWE WrestleMania X8, a video game designed on the former X-8 (artist), American artist and publisher X8 Music, a record label founded by Quadeca

Electronics Electrologica X8, a digital computer Roland Fantom-X8, a synthesizer keyboard by Roland Sony Ericsson Xperia X8, a smartphone Motorola X8 Mobile Computing System, a chipset

Transport Dassault 8X, a long range private jet made by Dassault Aviation Sehol X8, mid-size crossover SUV produced by JAC Motors X8 (New York City bus) X8, a Metrobus route Piaggio X8, an Italian-made motor scooter X8, IATA airline code for Ecuadorian airline Icaro Air

Other uses X8 protein domain Aerojet General X-8, a missile

See also 8X (disambiguation)