Khe or KHE may refer to:

Khē, Arabic letter Khe language, a language of Burkina Faso Khe, the name of the Nepali language among the Newar people Kaposiform hemangioendothelioma, a tumor Kherson International Airport, Kherson Oblast, Ukraine (IATA code) Khe, a raw fish dish of Koryo-saram cuisine based on the Korean dish hoe , village in Nadymsky District, Russia "Khé?", a 2024 song by Rauw Alejandro and Romeo Santos