CPQ may refer to:

Groups and politics Conseil du patronat du Québec (English: Quebec Council of Employers), an institution that promotes business interests in Quebec, Canada Conservative Party of Quebec, a Canadian political party in the province of Quebec

Science and technology Camphorquinone, main ingredient in dental resin fillings Carboxypeptidase Q, enzyme found in humans and encoded by CPQ gene Compaq, a defunct American technology company Configure, Price, and Quote, a category of software that helps companies offer and sell complex products Cucurbitadienol synthase, enzyme class found in plants 6-Chloro-2-(1-piperazinyl)quinoxaline, a serotonin reuptake inhibitor