Following is a list of notable non-profit organizations headquartered in the city of Jacksonville, Florida.
Jacksonville University Alfred I. duPont Testamentary Trust Alliance for the Lost Boys of Sudan Florida Baptist Health Boselli Foundation Brothers Fighting Against Mental Health Clara White Mission Communities In Schools of Jacksonville Community Hospice of Northeast Florida Dreams Come True FreshMinistries Gator Bowl Association HabiJax Hubbard House Jacksonville Arboretum & Gardens Jacksonville Civic Council Jacksonville Urban League MaliVai Washington Kids Foundation Nemours Children's Clinic Otis Smith Kids Foundation The Queer Trans Project Second Harvest North Florida St. Vincent's HealthCare Sulzbacher Center Tom Coughlin Jay Fund Foundation UF Health Jacksonville