Frattini is an Italian surname. Notable people with the surname include:
Angelo Frattini, sculptor Franco Frattini, politician Giovanni Frattini, mathematician Frattini argument Frattini subgroup Francesco Frattini, cyclist Pietro Frattini, Belfiore martyr Enrico Frattini, general Federico Frattini, scholar Gianfranco Frattini, architect and designer Cristiano Frattini, racing cyclist Davide Frattini, cyclist Víctor Frattini, basketball player Marius Frattini, rugby league footballer Eric Frattini, writer Pierpaolo Frattini, rower