Clerc is a French surname. Notable people with the surname include:
Albert Clerc, French chess player Aurélien Clerc, Swiss cyclist François Clerc, French footballer José Luis Clerc, Argentine tennis player Jub Clerc, Australian filmmaker Julien Clerc, French singer Laurent Clerc, teacher, co-founder of the first school for the deaf in North America Maurice Clerc (mathematician), French mathematician Maurice Clerc (organist), French organist Mialitiana Clerc (born 2001), Malagasy alpine skier Onésime Clerc, Swiss born Russian naturalist Vincent Clerc, French rugby union player
Fictional characters Jux Clerc, a character in Sign Gene: The First Deaf Superheroes Tom Clerc, a character in Sign Gene: The First Deaf Superheroes