The Montreal Laboratory () was a program established by the National Research Council of Canada in the 1940s during World War II to undertake nuclear research in collaboration with the United Kingdom, and to absorb some of the scientists and work of the Tube Alloys nuclear project in Britain. It became part of the Manhattan Project, and designed and built some of the world's first nuclear reactors.

After the Fall of France, some French scientists escaped to Britain with their stock of heavy water. They were temporarily installed in the Cavendish Laboratory at the University of Cambridge, where they worked on reactor design. The MAUD Committee was uncertain whether this was relevant to the main task of Tube Alloys, that of building an atomic bomb, although there remained a possibility that a reactor could be used to breed plutonium, which might be used in one. It therefore recommended that they be relocated to the United States, and co-located with the Manhattan Project's reactor effort. Due to American concerns about security (many of the scientists were foreign nationals) and patent claims by the French scientists and Imperial Chemical Industries (ICI), it was decided to relocate them to Canada instead.

The Canadian government agreed to the proposal, and the Montreal Laboratory was established in a house belonging to McGill University; it moved to permanent accommodation at the Université de Montréal in March 1943. The first eight laboratory staff arrived in Montreal at the end of 1942. These were Bertrand Goldschmidt and Pierre Auger from France, George Placzek from Czechoslovakia, S. G. Bauer from Switzerland, Friedrich Paneth and Hans von Halban from Austria, and R. E. Newell and F. R. Jackson from Britain. The Canadian contingent included George Volkoff, Bernice Weldon Sargent and George Laurence, and promising young Canadian scientists such as J. Carson Mark, Phil Wallace and Leo Yaffe.

Although Canada was a major source of uranium ore and heavy water, these were controlled by the Americans. Anglo-American cooperation broke down, denying the Montreal Laboratory scientists access to the materials they needed to build a reactor. In 1943, the Quebec Agreement merged Tube Alloys with the American Manhattan Project. The Americans agreed to help build the reactor. Scientists who were not British subjects left, and John Cockcroft became the new director of the Montreal Laboratory in May 1944. The Chalk River Laboratories opened in 1944, and the Montreal Laboratory was closed in July 1946. Two reactors were built at Chalk River. The small ZEEP went critical on 5 September 1945, and the larger NRX on 21 July 1947. NRX was for a time the most powerful research reactor in the world.

Early nuclear research in Canada

Canada has a long history of involvement with nuclear research, dating back to the pioneering work of Ernest Rutherford at McGill University in 1899. In 1940, George Laurence of the National Research Council (NRC) began experiments in Ottawa to measure neutron capture and nuclear fission in uranium to demonstrate the feasibility of a nuclear reactor. For that purpose, he obtained of uranium dioxide in paper bags from the Eldorado Mine at Port Radium in the Northwest Territories. For a neutron moderator, he used carbon in the form of petroleum coke. This was placed with the bags of uranium oxide in a large wooden bin lined with paraffin wax, another neutron moderator. A neutron source was added and a Geiger counter used to measure radioactivity.

The experiments continued in 1942, but were ultimately unsuccessful; the problems posed by impurities in the coke and uranium oxide had not been fully appreciated, and as a result too many neutrons were captured. But Laurence's efforts attracted some attention, and in the summer of 1940 he was visited by R. H. Fowler, the British scientific liaison officer in Canada. This was followed by a visit from John Cockcroft of the British Tizard Mission to the United States in the autumn. They brought news of the similar research being carried out under the supervision of the MAUD Committee in Britain and the National Defense Research Committee (NDRC) in the United States.

Fowler became the channel of communication between the NDRC and its counterparts in Britain and Canada. Through him, Laurence obtained an introduction to Lyman J. Briggs, the chairman of the NDRC's S-1 Uranium Committee, who supplied copies of American studies. On returning to England, Cockcroft arranged through Lord Melchett for Laurence to receive a $5,000 grant to continue his research. This payment was made by Imperial Chemical Industries (ICI) through a Canadian subsidiary. It had the desired side effect of impressing the Canadian authorities with the importance of Laurence's work.

French connection Laurence had chosen to use carbon instead of heavy water because it was cheaper and more readily available. A team of scientists in France that included Hans von Halban, Lew Kowarski, and Francis Perrin had been conducting similar experiments since 1939. By 1940, they had decided to use heavy water as a moderator, and through the French Minister of Armaments obtained about from the Norsk Hydro hydroelectric station at Vemork in Norway. After the Fall of France, they had escaped to Britain with their stock of heavy water. They were temporarily installed in the Cavendish Laboratory at the University of Cambridge but, believing that Britain would soon fall as well, were eager to relocate to the United States or Canada.

Canada was an alternative source of heavy water. Cominco had been involved in heavy water research since 1934, and produced it at its smelting plant in Trail, British Columbia. On 26 February 1941, the NRC inquired about its ability to produce heavy water. This was followed on 23 July by a letter from Hugh Taylor, a British-born scientist working at Princeton University, on behalf of the Office of Scientific Research and Development (OSRD). Taylor offered a NDRC contract to produce , for which the NDRC was prepared to pay $5 per pound for low-grade and $10 for high-grade heavy water. At the time it was selling for up to $1,130 per pound.

Cominco's president, Selwyn G. Blaylock, was cautious. There might be no post-war demand for heavy water, and the patent on the process was held by Albert Edgar Knowles, so a profit-sharing agreement would be required. In response, Taylor offered $20,000 for plant modifications. There the matter rested until 6 December, when Blaylock had a meeting with the British physicist G. I. Higson, who informed him that Taylor had become discouraged with Cominco, and had decided to find another source of heavy water. Blaylock invited Taylor to visit Trail, which he did from 5 to 8 January 1942. The two soon found common ground. Blaylock agreed to produce heavy water at Trail, and quickly secured approval from the chairman of the board, Sir Edward Beatty. A contract was signed on 1 August 1942. The heavy water project became known as the P-9 Project in October 1942.

The French scientists made good progress on the design of an aqueous homogeneous reactor, but there were doubts that their work was relevant to the main task of the British Tube Alloys project, that of building an atomic bomb, and resources were tightly controlled in wartime Britain. There was a possibility that a reactor could be used to breed plutonium, but its use in a bomb seemed a remote possibility. The MAUD Committee therefore felt that they should relocate to America. It made sense to pool resources, and America had advantages, notably access to materials such as heavy water. American scientists such as Henry D. Smyth, Harold Urey and Hugh Taylor urged that the Cambridge team be sent to America. On the other hand, American officials had concerns about security, since only one of the six senior scientists in the Cambridge group was British, and about French patent claims. These included patents on controlling nuclear chain reactions, enriching uranium, and using deuterium as a neutron moderator. There were also two patent applications in conjunction with Egon Bretscher and Norman Feather on the production and use of plutonium. George Thomson, the chairman of the MAUD Committee, suggested a compromise: relocating the team to Canada.

Establishment The next step was to broach the matter with the Canadians. The Lord President, Sir John Anderson, as the minister responsible for Tube Alloys, wrote to the British High Commissioner to Canada, Malcolm MacDonald, who had been involved in Tube Alloys negotiations with Canada regarding Eldorado's uranium mine at Port Radium and its refinery in Port Hope, Ontario. On 19 February 1942, MacDonald, Thomson and Wallace Akers, the director of Tube Alloys, met with C. J. Mackenzie, the president of the NRC, who enthusiastically supported the proposal. The following day he took them to see C. D. Howe, the Minister of Munitions and Supply.

Howe cabled Anderson expressing the Canadian government's agreement in principle, but requesting a more detailed appraisal of the cost of the proposed laboratory. Sir John Anderson replied that he envisaged a laboratory with about 30 scientists and 25 laboratory assistants, of whom 22 scientists and 6 laboratory assistants would be sent from Britain. The estimated running cost was £60,000 per annum. He agreed that the costs and salaries would be divided between the British and Canadian governments, but the British share would come from a billion-dollar war gift from Canada. The Canadians found this acceptable. Howe and Mackenzie then travelled to London to finalise arrangements for the laboratory's governance. It was agreed that it would be run by a Policy Committee consisting of Howe and MacDonald and be administered by and funded through the NRC, with research directed by a Technical Committee chaired by Halban.

The Canadians decided that the new laboratory should be located in Montreal, where housing accommodation was easier to find than in wartime Ottawa. They hoped to have everything ready by 1 January 1943, but negotiations for laboratory space fell through. A search then commenced for an alternative location. Bertrand Goldschmidt, a French scientist who was already in Canada, ran into Henri Laugier, a French biologist who had been president of the Centre national de la recherche scientifique before the Fall of France, when he had escaped to Canada. Laugier suggested that they acquire some unused wings of a new building at the Université de Montréal, where he was now teaching. These had been earmarked for a medical school, but had never been equipped due to a lack of funds. The space was acquired, but considerable work was required to convert it into a laboratory, and it could not be made ready before mid-February 1943. Ernest Cormier, the university architect, drew up the plans.

The first eight staff arrived in Montreal at the end of 1942. These were Goldschmidt and Pierre Auger from France, George Placzek from Czechoslovakia, S. G. Bauer from Switzerland, Friedrich Paneth and Halban from Austria, and R. E. Newell and F. R. Jackson from Britain. The Battle of the Atlantic was still raging, and men and equipment, which travelled separately, were at risk from German U-boats. The scientists occupied a house at 3470 Simpson Street in downtown Montreal that belonged to McGill University. This soon became so crowded that bathrooms were used for offices, with the bath tubs used to store papers and books. They were relieved to move to the more spacious accommodation at the Université de Montréal in March. The laboratory grew to over 300 staff, about half of whom were Canadians recruited by Laurence.