QB may refer to:
Arts and entertainment Quantum Break, a 2016 video game Quest Beat, a video game label Quratulain Balouch, Pakistani singer Kyubey, antagonist of 2011 anime Puella Magi Madoka Magica
Places Qualicum Beach, Vancouver Island, Canada Quarry Bay, Hong Kong, China Quebec, a Canadian province Queens, a borough of New York City, US Queens Boulevard, a highway Queensbridge, Queens, a public housing project
Science and technology ATCvet code QB for Blood and blood forming organs, a section of the Anatomical Therapeutic Chemical Classification System QuickBASIC, a programming language QuickBooks, accounting software QBittorrent, a free and open-source BitTorrent client Quettabyte, the largest official unit of measurement for digital information.
Transport QB (New York City Subway service), a defunct transit service Quiet Birdmen, a secret club for male American aviators Sky Georgia (IATA:QB)
Other uses Quarterback, a position in American and Canadian football Queen's Bench (disambiguation), a name of some courts in England, Wales and Canada Quiz bowl, an academic quiz game
See also Cuby & the Blizzards 1992 QB1, the first known classical Kuiper belt object, now named Albion