Payen may refer to:

People Anselme Payen (1795–1878), French chemist Antoine Payen the Younger (1792–1853), Belgian painter, naturalist and collector Antoine Payen the Elder (1748–1798), Belgian architect Antoine Payen (animator) (1902–1985), French animator Louis Payen (real name Albert Liénard, 1875–1927), French librettist Nicolas Payen (also Nicolas Colin, c. 1512–1559), Franco-Flemish composer and choirmaster Nicolas Roland Payen (1914–2004), French aeronautical engineer, including a list of 'Payen' aircraft Pierre Payen (1914–2004), French editorial cartoonist and caricaturist Payen Talu (born 1951), Taiwanese politician

Other uses Payén (also known as Reserva Provincial La Payunia), a natural reserve in Argentina

See also Hugues de Payens (c. 1070–1136), co-founder and first Grand Master of the Knights Templar Pascal Payen-Appenzeller (born 1944), Franco-Swiss historian, poet and writer