Wrigglesworth is an English surname. Notable people with the surname include:

Billy Wrigglesworth (1912–1980), English footballer Brian Wrigglesworth (c. 1935 – 2015), rugby league footballer who played in the 1950s, 1960s and 1970s, and coached in the 1970s Ian Wrigglesworth (born 1939), British politician Ian Wrigglesworth (cricketer) (born 1967), Australian cricketer Tom Wrigglesworth (born 1976), English stand-up comedian Nadine Wrigglesworth (born 1990), English Strategic HR Professional Wrigglesworth, a member of the group Public Service Broadcasting

See also Geoff Wriglesworth, English rugby league footballer of the 1960s and 1970s