TPU or tpu may refer to:
Science and technology Tensor Processing Unit, a custom ASIC built by Google, tailored for their TensorFlow platform DEC Text Processing Utility, a language developed by Digital Equipment Corporation for developing text editors Thermoplastic polyurethane, a class of polyurethane plastics Transcranial pulsed ultrasound, a brain-stimulation technique
Other uses TACA Peru (ICAO code), an airline Tampuan language (ISO 639-3 language code) Tikapur Airport (IATA code), Nepal Tokyo Polytechnic University, Japan Tomsk Polytechnic University, Tomsk, Russia Troop Program Unit, an organizational component of the United States Army Reserve