Tooth and Nail may refer to:

Music Tooth & Nail (Billy Bragg album), 2013 Tooth and Nail (Dokken album) or the title song, 1984 Tooth and Nail (various artists album), featuring California punk bands, 1979 Tooth & Nail Records, an American record label T&N, originally Tooth and Nail, an American rock band "Tooth and Nail", a song by Foreigner from Agent Provocateur, 1984

Other uses Tooth and Nail (film), a 2007 horror film Tooth and Nail (novel), a 1992 novel by Ian Rankin Tooth and nail syndrome, a medical disorder

See also The Tooth and the Nail, a 2017 South Korean film