Papazoglou (Greek: Παπάζογλου) is a Greek surname. The name comes from the Greek papas (priest) and Turkish oglou (oğlu - son), literally meaning priest's son. Notable people with this surname include:

Men Anastasios Papazoglou (born 1988), Greek footballer Athanasios Papazoglou (born 1988), Greek footballer Leonidas Papazoglou (1872–1918), Greek photographer Michalis Papazoglou, Greek member of World War II resistance Nikos Papazoglou (1948–2011), Greek songwriter and singer Panagiotis Papazoglou, Greek mathematician (in his papers under the name Panos Papasoglu) Christopher Ryan (born 1950) (Born Christopher Papazoglou), British actor

Women Orania Papazoglou (1951–2019), real name of American writer Jane Haddam Fanula Papazoglu (1917–2001), Yugoslav historian