Giannakopoulos () is a Greek patronymic surname, meaning "son of Giannakis". The female version of the name is Giannakopoulou (Γιαννακοπούλου). Notable examples include:
Pavlos Giannakopoulos (1929–2018), Greek businessman Thanassis Giannakopoulos (c.1930–2019), Greek businessman, former chairman of Panathinaikos BC Dimitrios Giannakopoulos (born 1974), Greek businessman, current chairman of Panathinaikos BC Stelios Giannakopoulos (born 1974), Greek footballer Nadia Giannakopoulou (born 1977), Greek politician