P50, P-50, or P.50 may refer to:
Aircraft Grumman XP-50, an American twin-engine heavy fighter prototype of 1941 Percival P.50 Prince, a late 1940s British light transport aircraft Piaggio P.50, an Italian heavy bomber prototype of 1937–1938 Pottier P.50, a French racing aircraft developed in the late 1970s PZL.50 Jastrząb, a Polish fighter of the late 1930s
Automobiles Honda P50, a Japanese moped Peel P50, a Manx three-wheeled microcar Trabant P 50, an East German small car
Mathematics and science P50 (neuroscience), an auditory event-related potential recorded using EEG P50 (pressure), the partial pressure of a gas required to achieve 50% enzyme saturation ASCC1, activating signal cointegrator 1 complex subunit 1 Median, or fiftieth percentile
Other uses Huawei P50, a smartphone , a patrol vessel of the Indian Navy Kel-Tec P50, a semi-automatic pistol Papyrus 50, a New Testament manuscript Pauza P-50, a sniper rifle P50, a state regional road in Latvia
See also 50P (disambiguation)