José Machado may refer to:
José Machado (rower) (1927–2004), Portuguese Olympic rower José Ramón Machado Ventura (born 1930), vice-president of Cuba (2008–2013) José Machado (São Tomé and Príncipe), Portuguese governor of São Tomé and Príncipe (1955–56) José Manuel Machado (1756–1852), Spanish soldier, ranchero, early citizen of the pueblo of San Diego