TBR may refer to:

Tampa Bay Rays, a Major League Baseball team Tampa Bay Rowdies, a USL Championship soccer club Tree bisection and reconnection, a tree rearrangement algorithm in computational phylogenetics TBR, IATA code for Statesboro-Bulloch County Airport TBR1 (T-box, brain, 1), a transcription factor protein Teenage Bottlerocket, a punk rock band from Laramie, Wyoming Tennessee Board of Regents, a public university system

This Beautiful Republic, a Christian rock band from Toledo, Ohio Tick-borne rickettsiosis Tile-based rendering

Tommy Baldwin Racing, a NASCAR race team Torpedo bomber reconnaissance Tracheobronchial rupture, a type of tracheobronchial injury Tracy Beaker Returns, a 2010 CBBC show Trickle-bed reactor, a chemical reactor The Barnes Review, American far-right magazine