Spay may refer to:

Spaying, the neutering of a female animal Spay, Germany, a municipality in Rhineland-Palatinate, Germany Spay, Sarthe, a commune in the Sarthe departement, France SPAY, the ICAO airport code for Tnte. Gral. Gerardo Pérez Pinedo Airport in Atalaya, Peru

See also Spey (disambiguation)