major histocompatibility complex (human), class I, B18 Alleles B*1801 Alleles B*1802 Alleles B*1803 Structure (See HLA-B) Symbol(s) HLA-B EBI-HLA B*1801 EBI-HLA B*1802 EBI-HLA B*1803 Locus chr.6 6p21.31
HLA-B18 (B18) is an HLA-B serotype. The serotype identifies the more common HLA-B*18 gene products. (For terminology help see: HLA-serotype tutorial) B*1801, the most common allele is at highest frequencies in Northern Italy and the Balkans, a peak frequency distribution it shares with B*3501.
Serotype B*18:06 is one of the four B alleles that reacts with neither Bw4 nor Bw6. The others are B*46:01, B*55:03, and B*73:01.
+ B18 serotype recognition of Some HLA B*18 allele-group gene productsderived from IMGT/HLA B*18 B18 Sample allele % % size (N) 1801 96 1641 1802 90 31 1803 83 29
Allele frequencies + HLA B*1801 frequencies freq ref. Population (%) Italy North pop 116.7 Croatia11.3 Georgia Svaneti Svans11.3 Romanian11.3 Portugal South11.2 Singapore Riau Malay9.9 Bulgaria9.1 Israel Arab Druse8.5 Azores Central Islands8.0 Portugal Centre8.0 Finland7.8 Azores Santa Maria and Sao Miguel7.7 Czech Republic7.5 India Jalpaiguri Toto7.5 Iran Baloch7.1 Philippines Ivatan7.0 Thailand6.7 Tunisia6.7 Portugal North6.5 Zimbabwe Harare Shona6.4 Madeira6.2 Mexico Mestizos6.1 Kenya 5.9 Belgium5.1 Morocco Nador Metalsa Class I5.1 Singapore Javanese Indonesians5.1 Israel Ashkenazi and Non Ashkenazi Jews5.0 Uganda Kampala5.0 Kenya Nandi4.8 Oman4.7 Georgia Tbilisi Georgians4.6 Bulgaria Gipsy4.5 France South East4.3 Kenya Luo4.3 Ireland South4.2 Russia Arkhangelsk Pomors4.0 Azores Terceira Island3.9 Guinea Bissau3.8 India New Delhi3.8 Spain Eastern Andalusia Gipsy3.5 Australia New South Wales3.4 Georgia Tbilisi Kurds3.4 Zambia Lusaka3.4 Cameroon Yaounde2.7 Senegal Niokholo Mandenka2.7 Cameroon Beti2.3 Ivory Coast Akan Adiopodoume2.3 Sudanese2.3 Saudi Arabia Guraiat and Hail2.2 South African Natal Zulu2.0 Thailand2.0 India Mumbai Marathas1.9 New Caledonia1.9 Papua New Guinea Wanigela1.5 Cameroon Bamileke1.3
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