Giant Spider may refer to:
Species Giant house spider, common to Europe Giant wood spider, or Golden silk orb-weaver, found worldwide
Mythology, folklore and fiction Giant Spider (Middle Earth), also known as Great Spiders Any depiction of oversized spider – see Cultural depictions of spiders, including: Some depictions of Anansi from African folklore Tsuchigumo, aka ōgumo (大蜘蛛, "giant spider"), a derogatory term and race of yōkai in Japanese folklore Pennywise from the novel IT Acromantulas from the novel series Harry Potter Giant spiders, a type of monster in Dungeons & Dragons role playing game
See also The Giant Spider Invasion, a 1975 sci-fi film Big Ass Spider!, a 2013 sci-fi comedy horror film