Seyler is a surname, and may refer to:
Seyler family, a Swiss-German family of artists and bankers, including Abel Seyler (1730–1801), Swiss theatre director Friederike Sophie Seyler (1737/38–1789), German actress and librettist Ludwig Edwin Seyler (1758–1836), German banker Seyler theatrical company Berenberg-Gossler-Seyler banking dynasty Athene Seyler (1889–1990), English actress Harry E. Seyler (1908–1994), American politician and educator Tomas Seyler (born 1974), German darts player
See also Hoppe-Seyler Seiler Sailer (disambiguation)