The year 1661 in science and technology involved some significant events.
Biology Marcello Malpighi is the first to observe and correctly describe capillaries when he discovers them in a frog's lung.
Chemistry Robert Boyle's The Sceptical Chymist is published in London.
Environment c. May 1 – John Evelyn's pamphlet Fumifugium is one of the earliest descriptions of air pollution.
Publications Abraham Cowley's pamphlet The Advancement of Experimental Philosophy. Johann Sperling's handbook Zoologia physica (posthumous).
Births May 3 – Antonio Vallisneri, Italian physician and natural scientist (died 1730) June 7 – Guillaume François Antoine, Marquis de l'Hôpital, French mathematician (died 1704) December 18 – Christopher Polhem, Swedish scientist and inventor (died 1751) approx. date – Alida Withoos, Dutch botanical artist (died 1730)
Events Isaac Newton is admitted to Trinity College, Cambridge, as a sizar (June)
Deaths October – Gérard Desargues, French geometer (born 1591)
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