George Knox may refer to:

George Knox (MP, died 1827) (1765–1827), Irish member of the United Kingdom parliament Sir George Edward Knox (1845–1922), British judge in India Sir George Hodges Knox (1885–1960), Australian politician George L. Knox (1841–1927), American escaped slave, activist, publisher and author George L. Knox II (1916–1964), U.S. Army Air Force officer and Tuskegee airman George William Knox (1853–1912), American theologian George Williams Knox (1838–1894), British soldier George A. Knox, zoologist and namesake of Mount Knox

See also Knox (surname)