A22 or A-22 is a three-character acronym that may refer to:
Vehicles A 22 (keelboat), a sailing yacht A-22 Maryland, an American light bomber of World War II manufactured by Glenn L. Martin Company Aero A.22, a Czech civil utility aircraft built during the 1920s Aeroprakt A-22, a Ukrainian ultralight aircraft Arrows A22, a Formula One car Fiat A.22, a piston aero-engine used on the 1925 Italian aircraft Ansaldo A.120 IVL A.22 Hansa, a 1922 Finnish license copy of the German two-seat, low winged single-engined seaplane Hansa-Brandenburg W.33 MAN A22, internal code for the NLxx3F low-floor single-deck bus chassis built by MAN
Biomedicine British NVC community A22 (Littorella uniflora - Lobelia dortmanna community), a plant community Anthrax (ICD-10 code A22) A22 (antibiotic) (S-[3,4-dichlorobenzyl] isothiourea hydrochloride)
Others A22 Sports Management, company aiming to create a European Super League in association football List of A22 roads English Opening, Encyclopaedia of Chess Openings code