Sean Byrne may refer to:
Footballers Sean Byrne (Irish footballer) (fl. 1920s and 1930s), Irish soccer player Sean Byrne (New Zealand footballer) (1955–2003), New Zealand international football player
Others Sean Byrne (filmmaker), Australian filmmaker Seán Byrne (politician) (1937–2018), Irish Fianna Fáil politician, TD 1982–1987, Senator 1989–1997 John "Sean" Byrne (1946–2008), Irish-born American musician
See also Sean Burns (disambiguation) Shaun Byrne (disambiguation)