Six ships of the British Royal Navy, and four tenders of the RNVR, have been named HMS Isis, after the Egyptian goddess Isis.
The first Isis was a 50-gun fourth rate probably launched in 1744 as . The second was the French ship captured in 1747 and converted to a 50-gun fourth-rate, continuing in use until 1766. The third was a 50-gun fourth rate launched in 1774, and broken up in 1810. The fourth was a 50-gun fourth rate launched in 1819, hulked in 1861 and sold 1867. The fifth was an protected cruiser in use from 1896 to 1920. The sixth was an launched in 1936. HMS Isis (M2010) was a launched in 1955 as HMS Cradley, renamed HMS Isis in 1963 and sold 1982.