William Guthrie may refer to: William Guthrie (boxer) (born 1967), American boxer William Guthrie (historian) (1708–1770), Scottish writer and journalist William Guthrie (politician) (1884–1954), Canadian politician William Guthrie (minister) (1620–1665), Scottish Presbyterian minister and author William A. Guthrie (1846–1916), American lawyer and politician William Dameron Guthrie (1859–1935), American lawyer W. K. C. Guthrie (William Keith Chambers Guthrie, 1906–1981), Scottish classical scholar and philosophy professor William Norman Guthrie (1868–1944), American clergyman William Tyrone Guthrie (1900–1971), English theatre director