Cagle is an American surname resulting from the Anglicization of the German surname Kegel. Notable people with the surname include:
A. M. Cagle (1884–1968), American composer Brett Cagle (born 1962), American religious leader Casey Cagle (born 1966), American politician Chris Cagle (born 1968), American country music singer Chris Cagle (American football) (1905–1942), American football player Daryl Cagle (born 1956), American cartoonist Harold Cagle (1913–1977), American athlete Mary Cagle (born 1989), American webcomic artist Myrtle Cagle (1925–2019), American pilot and part of Mercury 13 Sandy Cagle (born 1957), American model Susan Justice (née Susan Cagle, born 1981), American pop-rock singer Susie Cagle, American journalist/cartoonist, daughter of Daryl Valerie Cagle (born 2002), American softball player Will Cagle (1938–2025), American racing driver Yvonne Cagle (born 1959), American astronaut
See also Cagle's map turtle, a species of turtle Chris Cagle, Chris Cagle's self-titled album