Alexie can be either a surname or given name. Notable people with the name include:
Surname Robert Arthur Alexie (1957–2014), Canadian First Nations novelist and land claim negotiator Sherman Alexie (born 1966), American poet, writer, and filmmaker
Given name Alexie Gilmore (born 1976), American actress Alexie Glass-Kantor, Australian curator and writer
See also Alexy Alexey Aleksy