Hams Prairie (originally Ham's Prairie) is an unincorporated community in Callaway County, Missouri, United States. The town is located 5.5 miles south-southeast of Fulton on Missouri Route C. Mokane on the north edge of the Missouri River floodplain is six miles further south along Route C.Missouri Atlas & Gazetteer, DeLorme, 1st ed., 1998, p.38

Hams Prairie is named for Rev. John Ham, a Methodist minister who arrived in Callaway County in 1815 and cut his name on a tree at the edge of the prairie one year later.A Short History of Callaway County by Ovid Bell, p.3, and History of Callaway County, p.113 and p.481, as cited by Kingdom of Callaway Historical Society: Other Communities , retrieved 14 January 2008. A post office called Hams Prairie was established in 1865, and remained in operation until 1907.

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