was a Japanese samurai of the Akamatsu clan during the Muromachi Period.Nussbaum, Louis-Frédéric. (2005). "Kaikitsu-no-hen," Japan encyclopedia, p. 456. Other sources say he was born in 1373.

Family Mitsusuke was the son of Akamatusu Yoshinori and father of Akamatsu Noriyasu.

Assassination of the Shogun and death In 1441, Mitsusuke killed the reigning Ashikaga shogunate, Ashikaga Yoshinori, in response to the Shogun's choice of one of his rivals, Akamatsu Sadaura, as head of the clan. In response, he was attacked by forces of the Yamana clan and the Hosokawa clan. In defeat, he was forced to commit suicide.

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