AF1 or AF-1 may refer to:

Air Force One, the air traffic callsign for the plane (if operated by the Air Force) that the President of the United States is aboard Arena Football One (2025), a new Arena football league in the US , the lead ship of her class of stores ships for the US Navy Air Force 1 (shoe), produced by Nike, Inc. Methyl fluoroacetate

See also Air Force One (disambiguation) First Air Force (1 AF), USAF numbered air force