Carbonyl reductase [NADPH] 3 is an enzyme that in humans is encoded by the CBR3 gene. The enzyme is a member of short chain dehydrogenase/reductase superfamily (SDR).
Carbonyl reductase 3 catalyzes the reduction of a large number of biologically and pharmacologically active carbonyl compounds to their corresponding alcohols. The enzyme is classified as a monomeric NADPH-dependent oxidoreductase. CBR3 contains three exons spanning 11.2 kilobases and is closely linked to another carbonyl reductase gene - CBR1.
See also Carbonyl reductase (NADPH) Dehydrogenase
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