Domon is a surname. Notable people with the surname include:
Alice Domon (1937–1977), French, Roman Catholic nun Jean-Siméon Domon (1774–1830), French general Ken Domon (1909 - 1990), Japanese photographer Marius Domon (born 2002), French rugby union player
Fictional characters Domon Kasshu, main character from the fictional anime and manga series G Gundam Bayle Domon, character in American author Robert Jordan's Wheel of Time series Naoki Domon (a.k.a. BlueRacer), one of the main heroes in Gekisou Sentai Carranger Asuka Domon, a character from Inazuma Eleven