A nuke is a nuclear weapon, a powerful bomb.
Nuke may also refer to:
Computing Nuke (computer), a denial-of-service attack Nuke (software), a visual effects application Nuke (video games), a spell or skill that can deal great damage Nuke (warez), flagging problems with pirated software Total data loss
Fictional uses Nuke (Counter-Strike), a 1999 multiplayer map Nuke (Marvel Comics), a 1986 supervillain Nuke (Squadron Supreme), a 1970s Marvel superhero "Nuke" LaLoosh, in the 1988 film Bull Durham Nuke, a narcotic in the 1990 film RoboCop 2 Luke Snyder and Noah Mayer, a 2007 supercouple in television series As the World Turns
See also Luke Littler, English darts player (nickname: The Nuke) Newk, a nickname Nuc, a small honeybee colony Nuuk, Greenland Nukem (disambiguation) Microwave oven, or cooking therein A US Navy sailor operating nuclear power plants; see Nuclear Power School