MOB-like protein phocein

MOB-like protein phocein is a protein that in humans is encoded by the MOB4 gene (previously MOBKL3). This protein is part of the STRIPAK complexes (striatin-interacting phosphatase and kinase) which are involved in phosphorylation and regulate various signaling pathways.

Function

This gene was identified based on its similarity with the mouse counterpart. Studies of the mouse counterpart suggest that the expression of this gene may be regulated during oocyte maturation and preimplantation following zygotic gene activation. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

Interactions

MOBKL3 has been shown to interact with:

CTTNBP2NL, CTTNBP2, FAM40A, PDCD10, PPP2CA, STK24, STK25, STK26, STRN3, STRN, and TRAF3IP3.

References

Further reading