Great Void can refer to:
Astronomy A "super void", large empty regions of spaces Boötes Void, a supervoid in Boötes constellation Giant Void, a supervoid in the Canes Venatici constellation CMB cold spot, a supervoid in Eridanus constellation Outer space in general
Other At the Edge of the Great Void, the nineteenth volume of the Valérian and Laureline series A region in the Crystalicum RPG card game "Eoarchaean: The Great Void", a song by The Ocean Collective, from the album Precambrian Greetings from the Great Void, an album from the Italian duo My Cat Is an Alien Purgatory in the after-life