Southern Exposure may refer to:

Southern Exposure (album), a 1993 album by Maceo Parker Southern Exposure, a 2007 album by Bill Leverty Southern Exposure (art space), a San Francisco non-profit art space Southern Exposure (festival), a three-day event, held annually in Greenville, South Carolina Southern Exposure (film), a 1934 short film, a musical parody of Uncle Tom's Cabin Southern Exposure (magazine), a political and cultural magazine published by the Institute for Southern Studies Southern exposure (terminology) Southern Exposure Seed Exchange, a seed company specializing in heirloom varieties Daffy's Southern Exposure, a 1942 short film