Charlotte, the largest city in the U.S. state of North Carolina, is the site of 70 completed high-rise buildings over , 9 of which stand taller than . The tallest building in the city is the Bank of America Corporate Center, which rises in Uptown Charlotte and was completed in 1992. It is also the tallest building in North Carolina and the 56th-tallest building in the United States. The second-tallest skyscraper in the city is 550 South Tryon, which rises and was completed in 2010. The Truist Center, completed in 2002 and rising , is the 3rd-tallest building in Charlotte. Nine of the ten tallest buildings in North Carolina are located in Charlotte.
The history of skyscrapers in the city began with the construction of the Independence Building in 1909. This building, which rose and 14 floors, is often regarded as the first skyscraper in Charlotte. Despite having been added to the National Register of Historic Places in 1978, it was demolished in 1981 to allow for the construction of One Independence Center. Charlotte's first building taller than was One South at The Plaza, completed in 1974. The project Queensbridge Collective will be composed of two skyscrapers, the first buildings outside Uptown to rise above . The residential tower broke ground May 24, 2023, and is expected to be completed at the end of 2025. The office tower was changed to be a mixed use building with of office space across the top 19 floors and 304 apartments across the lower floors. Overall, the Council on Tall Buildings and Urban Habitat ranks Charlotte's skyline (based on buildings over tall existing or under construction) 4th in the Southeastern United States (after Miami, Atlanta and Sunny Isles Beach), 6th in the Southern United States (after Miami, Houston, Dallas, Atlanta and Sunny Isles Beach), and 19th in the United States.
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Tallest buildings , there are 70 high-rise buildings in Charlotte that stand at least tall, based on standard height measurement. This height includes spires and architectural details but does not include antenna masts. This list includes only buildings that have been completed and not just Topped out.