FHL3

Four and a half LIM domains protein 3 is a protein that in humans is encoded by the FHL3 gene.

LIM proteins are defined by the possession of a highly conserved double zinc finger motif called the LIM domain.

Function

FHL3 plays a role in myogenesis,Cottle et al., J Cell Sci. 2007 Apr 15;120(Pt 8):1423-35. doi: 10.1242/jcs.004739 and also stimulates the development of neural crest by enhancing BMP signaling.Intracellular enhancement of BMP signaling by LIM-domain protein FHL3 controls spatiotemporal emergence of the neural crest driven by WNT signaling Mansour Alkobtawi, Patrick Pla, Anne H. Monsoro-Burq bioRxiv 711192; doi: https://doi.org/10.1101/711192

Interactions

FHL3 has been shown to interact with: CREB1, CTBP2, FHL2, ITGA7 and KLF3.

References

Further reading

External links