This is a table of volume of distribution (Vd) for various medication. For comparison, those with a Vd L/kg body weight of less than 0.2 are mainly distributed in blood plasma, 0.2-0.7 mostly in the extracellular fluid and those with more than 0.7 are distributed throughout total body water.
Medication Vd L/kg body weightheparin 0.05-0.1 Page 103 insulin 0.05-0.1warfarin 0.1-0.2sulfamethoxazole 0.1-0.2glibenclamide 0.1-0.2atenolol 0.1-0.2NXY-059 0.1-0.2 Estimated with a body weight of 70 kg.tubocurarine 0.2-0.4theophylline 0.4-0.7ethanol 0.7-0.9neostigmine 0.7-0.9phenytoin 0.7-0.9methotrexate 1-2indometacin 1-2paracetamol 1-2diazepam 1-2lidocaine 1-2glyceryl trinitrate 2-5morphine 2-5propranolol 2-5digoxin 2-5chlorpromazine 2-5nortriptyline 2-5chloroquine 200 Estimated with a body weight of 70 kg.
References & footnotes