Melchiorre may refer to:
As first name Melchiorre Cafà (1636–1667), Maltese sculptor Melchiore Cesarotti (1730–1808), Italian poet Melchiorre Delfico (caricaturist) (1825–1895), Italian caricaturist Melchiorre Delfico (economist) (1744–1835), Italian economist Melchiorre Gherardini (1607–1668), Italian painter Melchiorre Gioia (1767–1829), Italian philosopher and economist Melchiorre Grimaldi (died 1512), Italian Bishop Melchiorre Luise (1896–1967), Italian opera singer Melchiorre Martelli, regent of San Marino Melchiorre da Montalbano, Italian architect and sculptor Melchiorre Murenu (1803–1854), Sardinian poet Melchiorre Zoppio (1544–1634), Italian doctor and scholar
As surname Daniela Melchiorre (born 1970), Italian magistrate and politician Gene Melchiorre (1927–2019), American college basketball player Luigi Melchiorre (born 1859), Italian sculptor