Takemoto (written: , , or ) is a Japanese surname. Notable people with the surname include:

, Japanese voice actor , Japanese playwright and puppet theatre director Iwao Takamoto (1925–2007), American animator, television producer, and film director , Japanese manga artist , Japanese footballer and manager , Japanese artistic gymnast , Japanese politician , Japanese author and fashion designer Tina Takemoto, American artist , Japanese director of anime series , Japanese footballer , Japanese swimmer