Calcineurin B homologous protein 1 is a protein encoded in humans by the CHP1 gene (formerly CHP).
Function
The protein encoded by this gene is a phosphoprotein that binds to the sodium-hydrogen exchangers (NHEs). This protein serves as an essential cofactor which supports the physiological activity of NHE family members. It has protein sequence similarity to calcineurin B and it is also known to be an endogenous inhibitor of calcineurin activity.
Interactions Calcineurin B homologous protein 1 has been shown to interact with sodium-hydrogen antiporter 1, sodium-hydrogen antiporter 3, and sodium-hydrogen anti porter 9.
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