James McCallum may refer to:
James McCallum (cyclist) (born 1979), Scottish racing cyclist James McCallum (politician) (1806–1889), American Confederate politician James Henry McCallum (1893–1984), American missionary James Scott McCallum (born 1950), American businessman and former governor of Wisconsin James McCallum (died 2025), guitarist with The Chefs
See also James MacCallum (1860–1943), Canadian ophthalmologist and art collector